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A New Look at DepoDur For the Management Of Postoperative Pain
DepoDur (EKR Therapeutics), a single-injection, extended release (ER) formulation of epidural morphine, is designed to provide up to 48 hours of pain relief for surgical inpatients. The purpose of this educational monograph is to bring together pertinent findings from the pivotal trials and, more importantly, the accrued clinical experience with DepoDur in real-world practice since its 2004 FDA approval. Pending label changes, including the administration of an analgesic dose of bupivacaine at least 30 minutes prior to DepoDur, also offer the opportunity to consider standard of care with DepoDur in the landscape of postoperative pain management.
JULY, 2009 |
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Opioid-Based Management of Persistent and Breakthrough Pain
The primary objective of this program is to educate health care professionals
about a semi- structured approach to the opioid-based management
of persistent and breakthrough pain (BTP). Particular emphasis
will be placed on appropriate selection of patients for opioid therapy following
comprehensive evaluation of the underlying chronic pain disorder
and stratifi cation of potential risks for medication misuse. Through
a combination of evidence- and case-based discussions, the importance
of identifying opioid-tolerant patients will be discussed, as will the
need for continual assessment of therapeutic structure and efficacy.
MARCH, 2009 |
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Novel Therapeutic Options In the Treatment of Cognitive Decline
The aging population is at increased risk for folate deficiency, which may contribute to cognitive decline. Epidemiologic studies show that relative deficiencies of vitamin B12 and folate are associated with Alzheimer’s disease (AD), whereas independent case–control studies have established an association between elevated serum homocysteine (Hcy) levels and AD.
NOVEMBER, 2008 |
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An Update: The Use of Metaxalone in the Treatment of Low-Back Pain
Acute, painful musculoskeletal conditions,
such as low-back pain, are common clinical
problems that have traditionally been treated
with a combination of modalities, including
skeletal muscle relaxants. These acute conditions
can become chronic, leading to significant
suffering.
MAY, 2008 |
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Nonsurgical Spinal Decompression To Treat Chronic Low Back Pain
In most industrialized countries, chronic low back pain (LBP) is recognized as a widespread condition. Until recently, conventional wisdom held that most episodes of acute LBP are benign and self-limited, with 80% to 90% of attacks resolving in about 6 weeks and that 5% to 10% of patients who experience an episode of acute LBP go on to experience chronic back pain.
DECEMBER, 2007 |
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